Chef d'équipe: Pr. Ziani-Cherif Chewki 

Membres:

Nom	Prénom	Position (1)	Affiliation (2)	email
ZIANI-CHERIF	Chewki	Enseignant Permanent	UAB Tlemcen	chewki.zianicherif@univ-tlemcen.dz
MOSTEFA-KARA	Bachir	Enseignant Permanent	UAB Tlemcen	karabi_99@yahoo.fr
BENMEDDAH	Amel	Enseignant Permanent	Université Sidi-Belabbès	benmeddah_amel@yahoo.fr
DIB	Salima	Enseignant Permanent	UAB Tlemcen	rdibdz@yahoo.fr
HAMZI	Imene	Enseignant Permanent	UAB Tlemcen	imenehamzi13@yahoo.com
KHETTAR	Ibrahim	Doctorant	UAB Tlemcen	ib_khettar@yahoo.com
CHEBIEB	Assia	Doctorant	UAB Tlemcen	chebiebassia@gmail.com

 

AUTRE PERSONNEL:
Nom	Prénom	Position (1)	Affiliation (2)	email
TAFER née MEZIANE	Fadhila	Assistante Directeur	UAB Tlemcen	taferfadila@gmail.com
MOKRI	Fatéma Zahra	Ingénieur	UAB Tlemcen	mokrifatimazahra@gmail.com
HADJ ABDELKADER	Hanane	Ingénieur	UAB Tlemcen	hadjabdelkaderhanane15@gmail.com

Research, Publications & Reprints

Publications Equipe 5 (de 2016 à Aujourd’hui)

 

51. “Study of interaction in dual-species biofilm of Candida glabrata and Klebsiella pneumoniae co-isolated from peripheral venous catheter using Raman characterization mapping and machine learning algorithms.”.

Abdeselem Benahmed, Abdelfettah Seghir, Fayçal Dergal, Anisse Chiali, Zahia Boucherit-Otmani, Chewki Ziani-Cherif.

Microbial Pathogenesis 2025, 199, p107280.

      https://doi.org/10.1016/j.micpath.2025.107280

 

50. “Vilsmeier–Haack Reagent Catalyzed C4(sp2) ─ H Formylation in Thiophene Derivatives: Insights into Unexpected Fluorescence Properties.”

Hadjer Missoum, Yazid Datoussaid, Chewki Ziani-Cherif, Julio A. Seijas, M. Pilar Vazquez-Tato, and Noureddine Choukchou-Braham. ChemistrySelect 2024, 9, e202404963.

https://doi.org/10.1002/slct.202404963

 

49. “Improvement of a low-cost protocol for a simultaneous comparative evaluation of hydrolytic activity between sessile and planktonic cells: Candida albicans as a study model.”

Wafaa Kendila, Fayçal Dergal, Ikram Tefiani, Yassine Moustafa Mahdad, Zakaria Benladghem, Chewki Ziani-Cherif and Sidi Mohammed Lahbib Seddiki.

Biofouling, The Journal of Bioadhesion and Biofilm Research, 2024, Volume 40, Issue 7, Pages 431-445.

 https://doi.org/10.1080/08927014.2024.2376637

 

48. “Design, Synthesis, Molecular Docking, and ADME-Tox Investigations of Imidazo[1,2-a]Pyrimidines Derivatives as Antimicrobial Agents.”

Djamila Benzenine, Ismail Daoud, Nadia Aissaoui, Zahira Kibou, Julio A. Seijas, Pilar Vázquez-Tato, Chewki Ziani-Cherif, Lahcen Belarbi and Noureddine Choukchou-Braham.

Molecules 2024, 29, 5058.

https://doi.org/10.3390/molecules29215058

 

47. “Experimental And Theoretical Studies Of Aminothiophene Derivatives Inhibitors On Carbon Steel Corrosion In Perchloric Acid Medium. “

Yazid DATOUSSAID, Hadjer MISSOUM, Tarik ATTAR, Boulanouar MESSAOUDI, Abbes BENCHADLI, Esma CHOUKCHOU-BRAHAM, Noureddine Choukchou-Braham and Chewki ZIANI-CHERIF.

Rev. Roum. Chim., 2024, 69(3–4), 139–148.

https://doi: 10.33224/rrch.2024.69.3-4.04.

 

46. “Enhanced Photodegradation of Sulfamethoxazole Through Cutting-Edge Titania-Zirconia-Based Materials.”

Zineb Bensmaine, Sanaa El Korso, Adriana Isabel Moral-Rodríguez, Sumeya Bedrane, Chewki Ziani-Cherif, Agustín Francisco Pérez-Cadenas, Francisco Carrasco-Marín and Esther Bailón-García.

Catalysts 2024, 14, 784.

 https://doi.org/10.3390/catal14110784

 

45. “Flexible and Convergent Enantioselective Total Synthesis of (R)‑Juglanaloids A and B: Two Phthalide Spiro Alkaloids with Potential Alzheimer’s Disease Inhibitory Activity”

Ibrahim Khettar, Arianna Sinibaldi, Rosaria Schettini, Giorgio Gorini, Ayesha Siddiqa, Antonella Dentoni Litta, Francesco De Riccardis, Irene Izzo, and Giorgio Della Sala.

The Journal of Organic Chemistry. 2024, 89, 7255−7262.

https://doi.org/10.1021/acs.joc.4c00740

 

44. “A Cascade Synthesis of Indoles”

Assia Chebieb and Jin Kun Cha.

The Journal of Organic Chemistry 2024 89 (14), 10293-10298

https://doi.org/10.1021/acs.joc.4c01190

 

43. “Synthesis of Indoles from o‑Haloanilines”

Assia Chebieb, Young Gyu Kim, and Jin Kun Cha.

The Journal of Organic Chemistry 2023 88 (14), 10164-10170

https://doi.org/10.1021/acs.joc.3c01047

 

42. “Peptidomimetic-Based Asymmetric Catalysts”

Ibrahim Khettar, Alicja Malgorzata Araszczuk and Rosaria Schettini.

Catalysts 2023, 13, 244.

https://doi.org/10.3390/catal13020244

 

41. “Acanthus mollis L. Grown in Algeria Exhibits Potent Antioxidant Activity.”

Nadia FEKIH, Hocine ALLALI, Chewki ZIANI-CHERIF, Guido FLAMINI.

ACS Agric. Conspec. Sci. 2023, Vol. 88, No. 4 (301-306).

https://hrcak.srce.hr/file/450445

 

40. “Chemical Composition and Antioxidant, Anti-inflammatory and Antimicrobial Activities of the Essential Oil and its Major Component (Carlina oxide) of Carlina hispanica Roots from Western Algeria. “

Radja Achiri, Lyna Benhamidat, Imane Rihab Mami, Mohammed El Amine Dib, Nadia Aissaoui, Chewki Ziani Cherif, Hocine Ziani Cherif & Alain Muselli.

Journal of Essential Oil-Bearing Plants, 2021, 24:5, 1113-1124.

https://doi.org/10.1080/0972060X.2021.2005692

 

39. “Catalyzed reaction of enaminonitrile with primary amines by SbF3: synthesis of new 2-aminosubstituted-pyridine-fused δ-lactones “

Fadhila Salhi, Nawel Cheikh, Didier Villemin, Bachir Mostefa-Kara, Nathalie Bar, Karine Jarsalé, and Nourredine Choukchou-Braham

Arkivoc 2018, part V, pp65-74

https://doi.org/10.24820/ark.5550190.p010.495

 

38. “First Examples of Povarov Reaction of Cyclopentadienones”

Amel Benmeddah, Nathalie Bar, Didier Villemin, Jean-François Lohier, Bachir Mostefa-Kara, Rémi Legay

Helv. Chim. Acta 2018, 101, e1800023

https://doi.org/10.1002/hlca.201800023

 

37. “Highly selective solvent-free hydrogenation of pinenes to added-value cis-pinane

Hydrogénation hautement sélective des pinènes en cis-pinane, un produit à forte valeur ajoutée, sans utilisation de solvant. »

Fanta J. Ndongou Moutombi, Ayyoub Selka, Anne-Sylvie Fabiano-Tixier, Delphine Foucher, Olivier Clarisse, Farid Chemat, Mohamed Touaibia

Comptes Rendus Chimie Volume 21, Issue 11, November 2018, Pages 1035-1042

https://doi.org/10.1016/j.crci.2018.09.002

 

36. “Facile Heterocyclic Synthesis and Antibacterial Activity of Substituted Isoxazol-5(4H)-ones”

Ghaniya Ferouani, Amina Nacer, Nawel Ameur, Redouane Bachir, and Chewki Ziani-Cherif

Journal of the Chinese Chemical Society 27 December, 2017.

http://onlinelibrary.wiley.com/doi/10.1002/jccs.201700334/abstract

 

35. “A Comparative Study of Solvent-Free and Highly Efficient Pinene Hydrogenation over Pd on Carbon, Alumina, and Silica Supports”

Ayyoub Selka, Natalie A Levesque, Delphine Foucher, Olivier Clarisse, Farid Chemat, and Mohamed Touaibia

Organic Process Research & Development 2017, 21 (1), 60-64

https://doi.org/10.1021/acs.oprd.6b00344

 

34. “Solvent from forestry biomass. Pinane a stable terpene derived from pine tree byproducts to substitute n-hexane for the extraction of bioactive compounds”

Edinson Yara-Varón, A Selka, Anne-Sylvie Fabiano-Tixier, Merce Balcells, Ramon Canela-Garayoa, Antoine Bily, M Touaibia, Farid Chemat

Green Chemistry 2016, 18 (24), 6596-6608

https://doi.org/10.1039/C6GC02191C

 

33. “Solvent from forestry biomass. Pinane a stable terpene derived from pine tree byproducts to substitute n-hexane for the extraction of bioactive compounds”.

Yara-Varón, A. Selka, A. S. Fabiano-Tixier, M. Balcells, R. Canela-Garayoa, Antoine Bily, M. Touaibiac and F. Chemat.

Green Chemistry. (2016). First published on line October 4, 2016

doi: 10.1039/c6gc02191c

 

32. “Orthogonal Synthesis of Xeno Nucleic Acids”

Guillaume Fiers, Dalila Chouikhi, Laurence Oswald, Abdelaziz Al Ouahabi, Delphine Chan-Seng, Laurence Charles, and Jean-François Lutz.

Chem. Eur. J., 22 ,1–5 (2016)

doi : 10.1002/chem.201604386

 

31. “Synthesis, Characterization, and Catechol Oxidase Activity of Cu (II) Complexes Derived from New Imidazolidine Derivatized Ligands”.

Louhibi, N. Merad-Boussalah, I. Belfilali, L. Boukli-Hacene, C. Ziani-Cherif, S. El Kadiri, and R. Touzani

Proceeding of 2015 2nd Int’l Conference on Advances in Chemical, Biological & Environmental Engineering (ACBEE-2015). ISBN 978-93-84422-49-3

 

30. “Synthesis of Well-Defined Polystyrene Rink Amide Soluble Supports and Their Use in Peptide Synthesis”

Meryem Imane Amrane , Dalila Chouikhi , Nezha Badi , Jean-François Lutz

Macromol. Chem. Phys. 215(20), p1984-1990 (2014)

doi: 10.1002/macp.201400347

http://onlinelibrary.wiley.com/doi/10.1002/macp.201400347/full

 

29. “Out of Africa.Algeria is an unknown hotbed of chemistry"

Andrew Warmington & Chewki Ziani-Cherif.

Specialty Chemicals Magazine. Feb 2013 Online Issue.

 

28. «A serendipitous conversion of enaminolactone nitriles with primary amines: a new synthesis of substituted 2-aminopyridine derivatives»

Nawel Cheikh, Didier Villemin, Nathalie Bar, Jean-Francois Lohier, Nourredine Choukchou-Braham, Bachir Mostefa-Kara, Jana Sopkova

Tetrahedron 69, 1234-1247 (2013)

http://dx.doi.org/10.1016/j.tet.2012.10.108

 

27. «Two versatile routes towards Cerpegin and analogues: applications of a one pot reaction to new analogues of Cerpegin»

Didier Villemin, Nawel Cheikh, Liang Liao, Nathalie Bar, Jean-Francois Lohier, Jana Sopkova, Noureddine Choukchou-Braham, Bachir Mostefa-Kara 

Tetrahedron 68, 4906-4918 (2012)

doi:10.1016/j.tet.2012.03.057062 

 

26. «5,6-Dihydro-2H-pyranones and 5,6-dihydro-2H-pyridones and their derivatives modulate in vitro human T lymphocyte function»

Baba Hamed, A. Medjdoub, B. Mostefa Kara, H. Merzouk, D. Villemin, M. Narce

Mol Cell Biochem  360 : 23–33 (2012)

doi: 10.1007/s11010-011-1040-x

 

25. «Efficient synthesis of new butenolides by subsequent reactions: application forthe synthesis of original iminolactones, bis-iminolactones and bis-lactones»

Nawel Cheikh, Nathalie Bar, Nourredine Choukchou-Braham, Bachir Mostefa-Kara, Jean-François Lohier, Jana Sopkova, Didier Villemin

Tetrahedron 67, 1540-1551 (2011)

doi:10.1016/j.tet.2010.12.062

 

24.“Chemical Composition and Antifungal Activity of Aleppo Pine Essential Oil”

Abi-Ayad M., Abi-Ayad F.Z., Lazzouni H.A., Rebiahi S.A., Ziani-Cherif C., Bessiere

Journal of Medicinal Plants Research vol. 5(22), pp.5433-5436, (2011).

 

23. «Nouvelle voie de synthèse des 2-Aminopyridines»

Zahira Kibou, Nawel Cheikh, Noureddine Choukchou-Braham, Bachir Mostefa-Kara, Mohammed Benabdellah, Didier Villemin

Scientific Study & Research. Chemistry & Chemical Engineering, Biotechnology, Food Industry 12 (2), pp. 121–126 (2011)

 

22. «Polyethylene glycol (PEG 300) and water-ethanol as benign solvent systems for the synthesis of new of 2-hydroxynaphthalen-1(4H)-ones»

Villemin, M Benabdellah, N. Choukchou-Braham and B. Mostefa-Kara

Synthetic Communications, 40 (20) : 3109-3118 (2010)      

doi: 10.1080/00397911003797916

 

21. «A Green Route for Synthesis of New 1, 2-Naphthoquinomethane acetonitriles in Water»

Villemin, M Benabdellah, M.N. Rahmoun, N. Choukchou-Braham and B. Mostefa-Kara

Synthetic Communications, 40 (23) : 3514-3521 (2010)      

doi: 10.1080/00397910903457340

 

20. “Antimicrobial Screening of the Algerian Lawsonia Inermis(henna)”

M.N.Rahmoun, M.Benabdallah, D. Villemin, K.Boucherit, B.Mostefa-Kara, C.Ziani-Cherif and N.Choukchou-Braham

Der Pharma Chemica, Vol2, No.6, pp320-326 (2010)

 

19. “New Chemical Tools for the assessment of Hemolytic Anemia Induced by Naphtoquinones”

Mostefa-Kara, C. Ziani-Cherif, M. Benabdallah, N.M. Rahmoun, D. Villemin, N. Choukchou-Braham and K. Boucherit

Der Pharma Chemica,Vol 2, No.1, pp 14-21 (2010)

 

18. “Theoretical Study of the Inhibition of β-Secretase”

I.Abdelli, S.Sari, C.Ziani-Cherif and S.Ghalem

Asian Journal of Chemistry, Vol 19, No.7, pp5407-5416 (2007)

 

17. «Prediction of the reactivity of 2(5H)-furanones as potential dienophiles in Diels-Alder reactions using philicity indexes»

Benmeddah, S.M. Mekelleche, W. Benchouk, B. Mostefa-kara, D. Villemin.

Journal of Molecular Structure: THEOCHEM 821, p42–46 (2007)

doi:10.1016/j.theochem.2007.06.018

 

16. "Base-promoted Reactions in Ionic Liquid Solvent: Synthesis of Butenolides"

Didier Villemin, Bachir Mostefa-Kara, Nathalie Bar, Noureddine Choukchou-Braham, Nawel Cheikh, Amel Benmeddah, Hassan Hazimeh and Chewki Ziani-Cherif.

Letters in Organic Chemistry, vol 3: (7), pp558-559 (2006)

doi: 10.2174/157017806778341807

 

15. "Gamma-Secretase as a Pharmacological Target in Alzheimer Disease Research. When, Why and How ?"

Chewki Ziani-Cherif, Bachir Mostefa-Kara, Fatima Z. Brixi-Gormat.

Current Pharmaceutical Design, vol 12 : (33), pp4313-4335 (2006)

doi: 10.2174/138161206778792994

 

14. «Solvent-free reaction on KF-alumina under microwave : serendipitous one-pot domino synthesis of new isobenzofuran-1(3H)-ones from alpha-hydroxyketones»

Villemin, N. Cheikh, B. Mostefa-Kara, N. Bar, N. Choukchou-Braham and M.A. Didi

Tetrahedron Letters, 47, 31 : 5519-5521 (2006)

 

13. «Synthèse Cascade en milieu basique de Lactones. Application à la synthèse de la Cerpegine et d’Isobenzofuranones»

Villemin, L. Liao, N. Bar, N. Cheikh, B. Mostefa-Kara, N. Choukchou-Braham and M.A. Didi

Scientific Study & Research, Vol II(4) : 885-891 (2006)

 

12. «A Case of Pictet-Spengler Revisited : Application to the Synthesis of Dihydroisocoumarin»

Choukchou-Braham, B. Mostefa-Kara, N. Cheikh, M.A. Didi and D. Villemin

Synthetic Communications, 35(2) : 169-178 (2005)

http://dx.doi.org/10.1081/SCC-200048399

 

11. "Peptide-based, irreversible inhibitors of gamma-secretase activity"
Siân C. Piper, Zareen Amtul, Laura Galiñanes-Garcia, Victor G. Howard, Chewki Ziani-Cherif, Chris McLendon, Marjorie J.  Rochette, Abdul Fauq, Todd E. Golde, M. Paul. Murphy.

Biochemical and Biophysical Research Communications, vol 305, pp529-533 (2003)

http://dx.doi.org/10.1016/S0006-291X(03)00828-3

 

10. “[4 + 3] Cycloaddition of aminoallylcations with 1,3-dienes: 11-oxatricyclo[ 11-Oxatricyclo[4.3.1.1]undec-3-en-10-one,(1α,2β,5β,6α)-]”

Jonghoon Oh, Chewki Ziani-Cherif, Jong-Ryoo Choi, and Jin Kun Cha

Organic Syntheses, Coll. Vol. 10, p.584 (2004); Vol. 78, p.212 (2002).

doi: 10.15227/orgsyn.078.0212

 

09. “A novel Gamma Secretase assay Based on detection of the Putative C-Terminal Fragment-Gamma Of APP”

Inga Pinnix, Usha Musunuru, Han Tan, Arati Skidharan, Todd E. Golde, Christopher Eckman, Chewki Ziani-Cherif, Luisa Onstead, Kumar Sambamurti

Journal of Biological Chemistry, vol 276: (1), pp481-487 (2001).

doi:10.1074/jbc.M005968200

 

08. “Cell Free Assays For g-Secretase Activity”

Chris. McLendon, TianPei Xin, Chewki Ziani-cherif, M. P. Murphy, Kirk A. Findlay, Patrick A. Lewis, Inga Pinnix, Kumar Sambamurti, Rong Wang, Abdul Fauq, Todd E. Golde

FASEB Journal, vol 14, pp 2383-2386 (2000)

doi:10.1096/fj.00-0286fje

 

07. “Peptide nucleic acids targeted to angiotensinogen lower mRNA levels, blood pressure and angiotensin I levels in rats”

Tyler-McMahon,B.M., Stewart,J.A., Jansen,K., Ziani-Cherif,C., Fauq,A., E.Richelson

Journal of Clinical Pharmacology. vol 40, p1048 (2000)

 

06. “Molecular Targets for the inhibition of Aβ production”

Chris McLendon, Paul Murphy, Chewki Ziani-Cherif, Abdul Fauq, Todd E Golde

Neurobiology of Aging, Vol21, Suppl.1, p180 (May-June 2000)

doi: http://dx.doi.org/10.1016/S0197-4580(00)82147-8

 

05.“Synthesis of (S)- and (R)- enantiomers of p-(4-Hydroxybenzoyl)phenylalanine, useful photoaffinity labeling probes for peptide-protein binding sites"

Abdul H. Fauq, Chewki Ziani-Cherif and Elliott Richelson

Tetrahedron Asymmetry. vol 9, pp 2333-2338 (1998)

http://dx.doi.org/10.1016/S0957-4166(98)00229-8

 

04. “New [4+3] Cycloaddition Approach to Cis-2,8-Disubstituted Oxocanes"

Heejin Kim, Chewki Ziani-Cherif, Jonhoon Oh and Jin Kun Cha

Org. Chem. vol 60, pp792-793 (1995)

doi: 10.1021/jo00109a005

 

03. “Total Synthesis of Natural Gingerols, the Three Active Principles of Ginger"

Guy Solladie, Chewki Ziani-Cherif

Org. Chem. vol. 58, pp2181-2185 (1993).

doi: 10.1021/jo00060a038

 

02. “Total Synthesis of (-)-(R)-Yashabushiketol. “

Guy Solladie, Chewki Ziani-Cherif, Francis Jesser.

Tetrahedron Letters, Vol 33, pp931-934 (1992).

http://dx.doi.org/10.1016/S0040-4039(00)91579-X

 

01. “Asymmetric Synthesis of C-1-C-8 Fragment of Leukotriene B4 and C-11-C-20 Fragments of Leukotriene B4 and 12(S)-hydroxy-5,8, 14(E) Eicosatetraenoic Acid.”

Guy Solladie, Chafiq Hamdouchi, Chewki Ziani-Cherif.

Tetrahedron Asymmetry. vol 2, No.6, pp457-469 (1991).

http://dx.doi.org/10.1016/S0957-4166(00)82171-0

 

Chewki Ziani-Cherif

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Contact

Tel: (+213) 554 81 40 16

email: chewki.zianicherif@univ-tlemcen.dz